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For example, peptides and proteins like insulin may require a slightly acidic environment (pH 4.0–5.5) to remain stable, whereas drugs such as atropine tend to be more stable in a slightly basic environment (pH 7.5–8.5)

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They tested daily oral AOD 9604 at 1 mg, 5 mg, 10 mg, and 30 mg, with a placebo arm, over 12 weeks