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[29] However, oral formulations may have a combination of vitamin C, vitamin E, alpha-lipoic acid, N-acetyl cysteine, grape seed extract, etc
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For example, cultured astrocytes subjected to oxygen and glucose deprivation showed a decrease in mitochondrial membrane potential, possibly caused by the mitochondrial permeability transition pore (mtPTP) opening, which leads to a loss of intramitochondrial contents, mitochondrial respiration and ATP production [48]