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[DOI] [PMC free article] [PubMed] [Google Scholar] 115.Speliotes E.K., Butler J.L., Palmer C.D., Voight B.F., Hirschhorn J.N

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As an extension of the above, the brain’s high metabolic rate and oxygen consumption make it vulnerable to oxidative stress, which can lead to aging and neurodegenerative diseases like Alzheimer’s and Parkinson’s Disease