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However, with the more recently introduced SGLT2 inhibitors and GLP-1 receptor agonists having shown impressive cardiovascular risk reduction in addition to glycemic control efficacy, these newer agents may also be considered as first-line therapies in patients with pre-existing cardiovascular or renal disease (Garber 2020)

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These links include aflatoxins and liver cancer, red meat and/or processed meat and colorectal cancer, alcohol and gastrointestinal cancers, and beta-carotene supplements and lung cancer in smokers