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To further verify that MOR-expressing neurons in PVN mediate morphine-induced constipation, we constructed a Cre-dependent AAV virus expressing Oprm1 short-hairpin RNAs (shMOR) to induce MOR knockdown specifically in PVN Glu neurons

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SIZE:35ml

Thus, the immunomodulating effects of Semax described here, as well as its influence on the vascular system in conditions of ischemia, are likely to be key factors in the neuroprotective effects of the peptide